Abstract

Repeated sheep treatment with the anthelmintic drug benzimidazole (BZ) resulted in selection of genetically benzimidazole-resistant (BZ-R) nematodes, which code for a specific allele of isotype 1Beta-tubulin. The presence of this allele was tested in the Waikato ovine nematode, using an allele specific PCR. Two isotype allele specific oligomers for O. circumcincta (O.c.) Beta-tubulin gene were designed. The last base at the 3

AR, Lehrer, HE Kahn, J Kreitzer, H Gacitua, Y Mizrachi, and J Kali

Proceedings of the New Zealand Society of Animal Production, Volume 55, , 165-168, 1995